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Biblioteca (s) : |
INIA La Estanzuela; INIA Las Brujas. |
Fecha : |
21/12/2020 |
Actualizado : |
27/12/2020 |
Tipo de producción científica : |
Artículos en Revistas Agropecuarias |
Autor : |
GIORELLO, D.; DO CANTO, J.; REYNO, R.; LATTANZI, F. |
Afiliación : |
DIEGO GERMAN GIORELLO LEITES, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JAVIER DO CANTO FAGUNDEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RAFAEL ALEJANDRO REYNO PODESTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FERNANDO A. LATTANZI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Gramíneas perennes estivales. ¿Cómo integrarlas a nuestro sistema?. |
Complemento del título : |
Pasturas. |
Fecha de publicación : |
2020 |
Fuente / Imprenta : |
Revista INIA Uruguay, 2020, no.63, p.19-23. |
Serie : |
(Revista INIA; 63). |
ISSN : |
1510-9011 |
Idioma : |
Español |
Contenido : |
La utilización de gramíneas perennes estivales puede contribuir a una disminución de riesgos y costos en los sistemas ganaderos, aportando
estabilidad y diversificación en la base forrajera. El presente artículo aborda los principales aspectos a considerar al momento de definir su inclusión, la selección de especie, su instalación y manejo, entre otros. |
Thesagro : |
GRAMINEAS PERENNES; PASTURAS; SIEMBRA. |
Asunto categoría : |
A50 Investigación agraria |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/14886/1/Revista-INIA-63-Diciembre-2020-p-19-23.pdf
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Marc : |
LEADER 00952naa a2200217 a 4500 001 1061607 005 2020-12-27 008 2020 bl uuuu u00u1 u #d 022 $a1510-9011 100 1 $aGIORELLO, D. 245 $aGramíneas perennes estivales. ¿Cómo integrarlas a nuestro sistema?.$h[electronic resource] 260 $c2020 490 $a(Revista INIA; 63). 520 $aLa utilización de gramíneas perennes estivales puede contribuir a una disminución de riesgos y costos en los sistemas ganaderos, aportando estabilidad y diversificación en la base forrajera. El presente artículo aborda los principales aspectos a considerar al momento de definir su inclusión, la selección de especie, su instalación y manejo, entre otros. 650 $aGRAMINEAS PERENNES 650 $aPASTURAS 650 $aSIEMBRA 700 1 $aDO CANTO, J. 700 1 $aREYNO, R. 700 1 $aLATTANZI, F. 773 $tRevista INIA Uruguay, 2020, no.63, p.19-23.
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
30/08/2022 |
Actualizado : |
30/08/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
CARRACELAS, B.; NAVAJAS, E.; VERA, B.; CIAPPESONI, G. |
Afiliación : |
EMERITA BEATRIZ CARRACELAS MARQUEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ELLY ANA NAVAJAS VALENTINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; BRENDA VERA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CARLOS GABRIEL CIAPPESONI SCARONE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
Genome-wide association study of parasite resistance to gastrointestinal nematodes in Corriedale sheep. |
Fecha de publicación : |
2022 |
Fuente / Imprenta : |
Genes, 2022, vol. 13, issue 9, 1548. OPEN ACCESS. doi: https://doi.org/10.3390/genes13091548 |
ISSN : |
e-ISSN 2073-4425 |
DOI : |
10.3390/genes13091548 |
Idioma : |
Inglés |
Notas : |
Article history: Received 25 May 2022; Revised 19 August 2022; Accepted 23 August 2022; Published 27 August 2022.
Correspondence: gciappesoni@inia.org.uy -- Academic Editor: Qiuyue Liu.
License: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
This article belongs to the Collection Feature Papers in Animal Genetics and Genomics: https://www.mdpi.com/journal/genes/topical_collections/feature_paper_animal |
Contenido : |
ABSTRACT.- Selection of genetically resistant animals is one alternative to reduce the negative impact of gastrointestinal nematodes (GIN) on sheep production. The aim of this study was to identify genomic regions associated with GIN resistance in Corriedale sheep by single-step genome-wide association studies (ssGWAS) using 170, 507 and 50K single nucleotide polymorphisms (SNPs). Analysis included 19,547 lambs with faecal egg counts (FEC) records, a pedigree file of 40,056 animals and 454, 711 and 383 genotypes from 170, 507 and 50K SNPs, respectively. Genomic estimated breeding values (GEBV) were obtained with single-step genomic BLUP methodology (ssGBLUP), using a univariate animal model, which included contemporary group, type of birth and age of dam as class fixed effects and age at FEC recording as covariate. The SNP effects as wells as p-values were estimated with POSTGSF90 program. Significance level was defined by a chromosome-wise False Discovery Rate of 5%. Significant genomic regions were identified in chromosomes 1, 3, 12 and 19 with the 170 SNP set, in chromosomes 7, 12 and 24 using the 507 SNP chip and only in chromosome 7 with the 50K SNP chip. Candidate genes located in these regions, using Oar_v4.0 as reference genome, were TIMP3, TLR5, LEPR and TLR9 (170 SNPs), SYNDIG1L and MGRN1 (507 SNP chip) and INO80, TLN2, TSHR and EIF2AK4 (50K SNP chip). These results validate genomic regions associated with FEC previously identified in Corriedale and other breeds and report new candidate regions for further investigation. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. MenosABSTRACT.- Selection of genetically resistant animals is one alternative to reduce the negative impact of gastrointestinal nematodes (GIN) on sheep production. The aim of this study was to identify genomic regions associated with GIN resistance in Corriedale sheep by single-step genome-wide association studies (ssGWAS) using 170, 507 and 50K single nucleotide polymorphisms (SNPs). Analysis included 19,547 lambs with faecal egg counts (FEC) records, a pedigree file of 40,056 animals and 454, 711 and 383 genotypes from 170, 507 and 50K SNPs, respectively. Genomic estimated breeding values (GEBV) were obtained with single-step genomic BLUP methodology (ssGBLUP), using a univariate animal model, which included contemporary group, type of birth and age of dam as class fixed effects and age at FEC recording as covariate. The SNP effects as wells as p-values were estimated with POSTGSF90 program. Significance level was defined by a chromosome-wise False Discovery Rate of 5%. Significant genomic regions were identified in chromosomes 1, 3, 12 and 19 with the 170 SNP set, in chromosomes 7, 12 and 24 using the 507 SNP chip and only in chromosome 7 with the 50K SNP chip. Candidate genes located in these regions, using Oar_v4.0 as reference genome, were TIMP3, TLR5, LEPR and TLR9 (170 SNPs), SYNDIG1L and MGRN1 (507 SNP chip) and INO80, TLN2, TSHR and EIF2AK4 (50K SNP chip). These results validate genomic regions associated with FEC previously identified in Corriedale and other breeds an... Presentar Todo |
Palabras claves : |
FEC; Genomic regions; SsGWAS. |
Asunto categoría : |
L01 Ganadería |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16636/1/genes-13-01548-v2.pdf
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Marc : |
LEADER 02850naa a2200229 a 4500 001 1063548 005 2022-08-30 008 2022 bl uuuu u00u1 u #d 022 $ae-ISSN 2073-4425 024 7 $a10.3390/genes13091548$2DOI 100 1 $aCARRACELAS, B. 245 $aGenome-wide association study of parasite resistance to gastrointestinal nematodes in Corriedale sheep.$h[electronic resource] 260 $c2022 500 $aArticle history: Received 25 May 2022; Revised 19 August 2022; Accepted 23 August 2022; Published 27 August 2022. Correspondence: gciappesoni@inia.org.uy -- Academic Editor: Qiuyue Liu. License: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). This article belongs to the Collection Feature Papers in Animal Genetics and Genomics: https://www.mdpi.com/journal/genes/topical_collections/feature_paper_animal 520 $aABSTRACT.- Selection of genetically resistant animals is one alternative to reduce the negative impact of gastrointestinal nematodes (GIN) on sheep production. The aim of this study was to identify genomic regions associated with GIN resistance in Corriedale sheep by single-step genome-wide association studies (ssGWAS) using 170, 507 and 50K single nucleotide polymorphisms (SNPs). Analysis included 19,547 lambs with faecal egg counts (FEC) records, a pedigree file of 40,056 animals and 454, 711 and 383 genotypes from 170, 507 and 50K SNPs, respectively. Genomic estimated breeding values (GEBV) were obtained with single-step genomic BLUP methodology (ssGBLUP), using a univariate animal model, which included contemporary group, type of birth and age of dam as class fixed effects and age at FEC recording as covariate. The SNP effects as wells as p-values were estimated with POSTGSF90 program. Significance level was defined by a chromosome-wise False Discovery Rate of 5%. Significant genomic regions were identified in chromosomes 1, 3, 12 and 19 with the 170 SNP set, in chromosomes 7, 12 and 24 using the 507 SNP chip and only in chromosome 7 with the 50K SNP chip. Candidate genes located in these regions, using Oar_v4.0 as reference genome, were TIMP3, TLR5, LEPR and TLR9 (170 SNPs), SYNDIG1L and MGRN1 (507 SNP chip) and INO80, TLN2, TSHR and EIF2AK4 (50K SNP chip). These results validate genomic regions associated with FEC previously identified in Corriedale and other breeds and report new candidate regions for further investigation. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. 653 $aFEC 653 $aGenomic regions 653 $aSsGWAS 700 1 $aNAVAJAS, E. 700 1 $aVERA, B. 700 1 $aCIAPPESONI, G. 773 $tGenes, 2022, vol. 13, issue 9, 1548. OPEN ACCESS. doi: https://doi.org/10.3390/genes13091548
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